May 25, 2015

Claims and Responses to Common Challenges and Defenses in Driving While Impaired Cases NHTSA

Challenges and Defenses II
Claims and Responses to Common Challenges and Defenses in Driving While Impaired Cases
The National Traffic Law Center is a program of the National District Attorneys Association. This document was prepared under Cooperative Agreement Number DTNH22-05-H-05166 from the U.S. Department of Transportation, National Highway Traffic Safety Administration. Points of view or opinions in this document are those of the authors and do not necessarily represent the official position or policies of the Department of Transportation, NHTSA, or the National District Attorneys Association. i

TABLE OF CONTENTS Acknowledgements ...........................................................................................................iii Introduction ....................................................................................................................... v Confronting Defense Issues in Prescription and Over-the-Counter Drug DUIs ......... 1 The defendant is not guilty because he was using an over-the- counter or lawfully prescribed drug............................................................................... 1 The defendant was mistakenly or involuntarily intoxicated. ......................................... 2 The quantitative levels of the drug are below the therapeutic dose and therefore not capable of causing impairment. ............................................................... 3 The defendant was unconscious or cannot remember what happened due to the effects of Ambien and therefore not legally responsible for his actions. ...................... 4 Jurors may empathize with the defendant about the use of a legal drug. ...................... 6 Breath Testing Results: Defense Alternative Explanations .......................................... 8 Diabetes ......................................................................................................................... 8 Defendant has diabetes .......................................................................................... 11 GERD (Gastroesophageal Reflux Disease) ................................................................. 13 Defendant has GERD, which created an artificially high reading or inaccurate result on the breath-testing instrument. ................................................ 13 Challenges to Blood Draws and Test Results ................................................................ 17 The swab used to cleanse the skin prior to the blood draw contained alcohol and contaminated the sample. ........................................................ 17 The presence of clots in the blood sample artificially increased the reported alcohol concentration. ................................................................................... 18 ii Challenges to Blood Draws and Test Results (cont.) Improper package and storage of the blood caused the development of yeast (Candida albican,) artificially increasing the reported alcohol concentration (fermentation). ..........................................................................19 The State has not demonstrated that the gray top blood tubes used to draw the blood contained the proper chemicals to ensure a valid analysis. ...............................20 Serum and plasma have higher alcohol contents than whole blood. Because BAC is measured in terms of whole blood, the serum and plasma results are misleading. .....................................................................................20 The blood testing instrument measured and reported something other than ethyl alcohol and this artificially increased the reported BAC. ............................................21 The tubes used to collect the blood were expired, so the results cannot be trusted. .........................................................................................................22 Arterial blood is a much better indicator of actual BAC levels when compared to venous blood. ..........................................................................................22 The gray top tubes used to collect the blood samples were not FDA-approved. Therefore, the jury and/or judge should not trust the results. ......................................23 Measurement Uncertainty ...............................................................................................24 The chemical test results without an accompanying uncertainty measurement value are not scientifically reliable. .............................................................................25 The bare chemical test result without a confidence interval misleads the jury. ...........26 Challenges to the Source Code of Breath Testing Instruments ...................................28 The defense needs the source code in order to be assured of the accuracy of the breath test instrument and its results. .................................................28 The defendant has a right to discovery of the source code and the prosecution must produce it. ........................................................................................30 Resources and References ...............................................................................................32

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ACKNOWLEDGMENTS
This guide was created by the National Traffic Law Center of the National District Attorneys Association and is the result of a collaborative effort of the following traffic safety professionals:
L. Beth Barnes, Arizona Traffic Safety Resource Prosecutor, Assistant City Prosecutor, Phoenix, Arizona
Edward A. Berkovich, Utah Traffic Safety/Domestic Violence Resource Prosecutor
Brian Chodrow, Program Analyst, Impaired Driving Division, National Highway Traffic Safety Administration
Daniel M. Fox, California Traffic Safety Resource Prosecutor
Moses Garcia, Washington Traffic Safety Resource Prosecutor
William Lemons, Minnesota Traffic Safety Resource Prosecutor
Mark M. Neil, Senior Attorney, National Traffic Law Center of the National District Attorneys Association
Jared Olson, Idaho Traffic Safety Resource Prosecutor
R. Alexander Robinson, former Staff Attorney, National Traffic Law Center of the
National District Attorneys Association
Joanne E. Thomka, Program Director, National Traffic Law Center of the National
District Attorneys Association iv v

INTRODUCTION
DUI cases have become some of the most complex in the criminal justice system. As a result, defense challenges are being raised more frequently and are more procedural and scientific in nature. These challenges range from the initial law enforcement stop of the vehicle to the testing procedures used to determine alcohol concentration in blood, breath, and urine samples to possible alternative explanations for those results. This monograph was developed to assist prosecutors and law enforcement in understanding the nature of these challenges. It will assist prosecutors in formulating effective responses to these newer challenges and defenses and include drugged driving, alternative explanations to breath test results, blood draws and testing, scientific uncertainty, and computer source code discovery requests.
The National Traffic Law Center previously published Overcoming Impaired Driving Defenses, thanks to a contribution from a charitable foundation, discussing such defense challenges as invalid traffic stops, arrests and Miranda issues, as well as common trial tactics of attacking the investigation, such as driving observations, personal contact, field sobriety tests and breath testing. That monograph may be downloaded from the National District Attorneys Association Web site at www.ndaa.org.
The terms DUI (driving under the influence), DWI (driving while intoxicated or impaired) and OUI (operating under the influence) are considered interchangeable for the purposes of this publication. vi 1

Confronting Defense Issues in Prescription or Over-the-Counter Drug DUIs
When the topic of “drugged driving” comes up, most people think almost exclusively of the use of illicit or controlled substances by someone operating a motor vehicle. However, prescription or over-the-counter (OTC) drugs also impair a person’s ability to operate a motor vehicle in a safe and prudent manner. Both prescription and OTC drugs are known to cause mental and physical impairment, especially when multiple drugs are used in combination or drugs are mixed with alcohol.
CLAIM: The defendant is not guilty because he was using an over-the-counter or lawfully prescribed drug.
RESPONSE: Entitlement is not a legally recognized defense.
An entitlement defense encompasses the mens rea of “I didn’t do anything wrong, or at least I didn’t know that I was doing anything wrong.” It amounts to the defendant offering a seemingly valid excuse for his behavior. An entitlement defense occurs when the defendant presents a valid prescription or OTC purchase to the jury as justification for the medications found in his system. In doing so, the defendant asserts to the jury that he has done nothing unlawful by consuming the medicine and driving. Dissected: the defendant focuses the jury’s attention on the reason for the impairment and not on his decision to drive. He can justify the impairment but the prosecutor needs to point out that the defendant still can’t justify the decision to drive while impaired.
How a defendant came to be impaired is not an element of proof in a DUI case. However, the prosecutor should make strategic and tactical efforts to satisfy a jury’s curiosity of how impairment occurred. The prosecutor must also educate the jury that they must decide whether the defendant was impaired at the time of driving and not how he be-came impaired. It matters not that the defendant had a prescription or bought the medication over the counter. By so doing, this will negate the entitlement defense.
If the defendant alleges he possessed a prescription for the drug found in his sys- tem, the prosecutor may be able to request the defendant’s prescription records as part of pretrial discovery. If this type of discovery is allowed in the jurisdiction, the prosecutor should request the names and contact information of all doctors writing prescriptions for the defendant and a record of all the filled prescriptions at the time of the crime. The prosecution should actively counter any claim of doctor-patient confidentiality and HIPAA privacy by pointing out the appropriate HIPAA exception statutes (see 45CFR164.512) and the fact that the defendant’s intent to present such a defense creates an implied waiver of medical confidentiality. This information may help the prosecutor in answering the following questions:
• What was the length and depth of the defendant’s experience with the drugs found in his system at the time of arrest?
• Was the medicine being used in conjunction with other medicines? 2

• Did the defendant follow the directives of his doctor in taking the medication (dosage, timing, accompaniment, etc.)?
• Did the quantity of the medicine and its metabolites in the defendant’s system correlate to a proper dosage of the medicine in agreement with the defendant’s prescription(s)?
• Did the medicine come with explicit warning labels?
• Did the defendant receive any warnings from the doctor(s) or the pharmacist?
• Was the defendant’s long-term consumption pattern consistent, and did it keep pace with the doctor’s directives and prescription quantities?
• Did the defendant receive prescriptions from more than one health care provider? If so, were the providers aware of each other?
CLAIM: The defendant was mistakenly or involuntarily intoxicated.
RESPONSE: The defendant drove impaired.
The entitlement defense borrows from and mixes elements of the defenses of mistake and involuntary intoxication. By asserting a privilege to take the medicine, the defendant implies that the impairment occurred unintentionally - that it was a mistake. It also implies a lack of knowledge as to the impairing nature of the substance - that the intoxication was involuntary: “I didn’t mean to do it” and “I didn’t know it would do that to me.”
To prevail on a mistake defense, the defendant must convince the jury that his belief that he was not impaired was reasonable. The defendant’s mistaken belief that a prescription entitled him to drive while under the influence is not the fact in question. Nor is the defendant’s mistaken belief that he wasn’t violating the law. He must be mistaken as to the fact of his impaired state and his belief has to be both actual and reasonable. True, impaired people often believe that they are okay to drive. However, most jurors, when presented with the facts and observed behavior of the defendant by law enforcement officers, often find such beliefs to be unreasonable. One need only analogize this to an alcohol DUI to see how rigorous a burden the defendant faces in this type of defense.
Similarly, in drugged driving cases, the defense of involuntary intoxication contains two key flaws: (1) the crime of DUI does not require proof that the defendant in- tended to become intoxicated, and (2) involuntary refers to the act of consuming the in- toxicant, not the outcome of the consumption.
A person voluntarily consuming a substance with knowledge that it can impair does not give rise to the defense of involuntary intoxication. Involuntary intoxication arises when a person unknowingly consumes an intoxicant, usually as a result of fraud, trickery, or deceit. Defendants may be hard pressed to present credible evidence that the drug pro-cured over the counter or as a result of visiting a healthcare practitioner and then a pharmacy was subsequently consumed involuntarily. 3

Some defendants seek to preserve the viability of the involuntary intoxication defense by asserting ignorance as to the intoxicating properties of the drug. This type of defense is often presented in argument without any testimony from the defendant. Unless the defendant testifies personally as to their subjective belief, the defense attorney should not be permitted to argue this defense at any point in the case.
If the defendant does testify, the prosecutor should be prepared to confront the reasonableness of the defendant’s ignorance. The prosecutor should gather as much evidence as possible pertaining to the medical reason for the prescription (pain relief, muscle relaxation, insomnia, etc.) or OTC medicine, any warnings that accompany the medicine (packaging, inserts, doctor’s statements, pharmacist advisements, etc.) as well as the defendant’s past experience with the medicine.
CLAIM: The quantitative levels of the drug are below the therapeutic dose and therefore not capable of causing impairment.
RESPONSE: Therapeutic doses of medication may equate to impairment.
Typically, this defense arises when the defendant introduces evidence that the amount of the drug found in their system would not produce impairment. The defense is raised almost exclusively where the quantitative level of the drug measures near or below the minimum therapeutic dosage level. Many jurors may be under the misconception that taking a prescription or OTC drug as part of a medical regime will make a person “all better” or normal. The concept that these drugs might cause impairment may be out- side their daily understanding of drugs and how they work.
To effectively combat this defense and jurors’ lack of understanding, a prosecutor needs a working knowledge of the drug and its effects. A drug handbook, the Physician Desk Reference (PDR) or a similar publication can be a good source for this information. Likewise, procure any available pharmacy literature, inserts and packaging that come with a prescription or OTC drugs.
If available, speak with a toxicologist about the effects of the drug, what the quantitative amount means and what the lab protocols were for testing. Review with the toxicologist whether the therapeutic or even lower dosage of the drug could have an impairing effect and what those effects may be. Then review the test results specific to the defendant and what, if any, impairing effect that amount may have. Some drugs, by their very nature and even when taken properly, can cause impairment for driving. For ex- ample, sleep aids taken at a therapeutic level cause sleep.
If possible, involve a drug recognition expert (DRE) in the case. A DRE’s ability to describe drug impairment and driving behavior may significantly assist in the presentation of the prosecutor’s case. The information obtained from the toxicologist can be tied together with the DRE assessment and signs of impairment observed by the law enforcement officers and others. 4

CLAIM: The defendant was unconscious or cannot remember what happened due to the effects of Ambien and therefore not legally responsible for his actions.
RESPONSE: Amnesia by the defendant is not unconsciousness and is not a legal defense.
Ambien is zolpidem tartrate,1 which is marketed as both Ambien and Ambien CR. Both promote the rapid onset of sleep (usually within 20 to 30 minutes of consumption). Ambien CR (controlled release) is designed to assist a person to fall asleep and stay asleep. Ambien CR is designed to wear off within six or seven hours and thereby permit the person to awaken normally.
Understanding the Ambien Defense
The crux of the Ambien defense is that the defendant was unconscious, and thus unable to make a conscious decision, at the time he chose to drive. Unconsciousness ne-gates the mens rea element required in almost all crimes.
The manufacturer’s prescription inserts for Ambien CR states:
Complex behaviors such as "sleep-driving" (i.e., driving while not fully awake after ingestion of a sedative-hypnotic, with amnesia for the event) have been reported with sedative-hypnotics, including [zolpidem. These events can occur in sedative-hypnotic- naive as well as in sedative-hypnotic-experienced persons. Although behaviors such as "sleep-driving" may occur with Ambien alone at therapeutic doses, the use of alcohol and other CNS depressants with Ambien appears to increase the risk of such behaviors, as does the use of Ambien at doses exceeding the maximum recommended dose.
As noted in the insert, complex behaviors may occur when Ambien is used appropriately; however, such behaviors increase when it is used improperly. Therefore, the prosecutor needs to watch for evidence indicating the improper use of Ambien whenever the defense is raised. Any improper use negates an otherwise legitimate defense; that the person took the drug as prescribed and did not consume any alcohol or other CNS depressants.
1 Ambien and Ambien CR are registered trademarks of Sanofi-Aventis U.S. LLC. 5

The defense may claim that a defendant’s lack of memory is a result of unconsciousness. The defense, however, often overlooks the distinction between unconscious- ness and amnesia. According to Black’s Law Dictionary, unconsciousness is defined as “being without awareness; not conscious. A person who commits a criminal act while unconscious may be relieved from liability for the act.”2 In other words, the person is unaware that he is performing an action. Amnesia, on the other hand, is defined in the Merriam-Webster’s Medical Dictionary as “a loss of memory sometimes including the memory of personal identity due to brain injury, shock, fatigue, repression, or illness or sometimes induced by anesthesia. It may also be a gap in one’s memory.”3 Unconscious-ness may be a legal defense; amnesia may not.
The prosecution bears the burden of proving consciousness. Fortunately conscious-ness can be proven rather easily. The arresting officer should be able to give the follow-ing information as it pertains to the defendant’s actions and responses:
• Was the defendant aware of his surroundings?
• Was he capable of answering questions in a cogent and logical manner or was he confused and unresponsive?
• Was the defendant able to identify himself and provide pertinent and accurate personal information?
• Was the defendant able to follow directions?
Upon a showing of consciousness by the prosecution, the defense bears the burden of producing evidence suggesting unconsciousness. Often, the defense offers little more than the self-serving declarations of the defendant claiming to have taken Ambien and be-ing unable to recall anything else afterwards. The defendant’s claim of no recollection is amnesia, not unconsciousness. If the defense fails to put forth sufficient proof of un-consciousness, then no unconsciousness defense should be presented to the jury for consideration.
Should the defense succeed in making a showing of unconsciousness, most States would require the defendant’s unconsciousness be the result of involuntary intoxication. Recall that involuntary relates to the consumption of the intoxicant, not to the consequences-es that result from the consumption. The prosecutor should point out that the defendant went to a doctor, received a prescription, had it filled at a pharmacy, may have had the op-opportunity to speak directly with a pharmacist, and then consumed the drug for the ex-pressed purpose of sleeping. That information could negate a defense claim that he did not know that it could make him perform acts while asleep.
The law generally does not recognize voluntarily intoxication to the point of un- conscious as a defense. If it did, then every instance in which a person consumed alcohol to the point of blacking out and then got behind the wheel would be perfectly defensible.
2 Black’s Law Dictionary, 8th Edition.
3 See, Merriam-Webster’s Medical Dictionary, 2012 6

Additional information that the prosecutor should examine if an Ambien defense is raised includes the following:
• Did the defendant take the Ambien in combination with other drugs or with alcohol?
• When did the defendant take the Ambien in relation to the time of operation of the vehicle?
• Has the defendant had prior episodes of somnambulism (sleepwalking) while on Ambien?
• Has the defendant consumed Ambien in excess of the designated dosage?
ISSUE: Jurors may empathize with the defendant about the use of a legal drug.
RESPONSE: Address the issue of “Identification Bias” during voir dire.
Cases involving drivers impaired by “legal” or licit drugs present some of the most difficult jury and proof issues a prosecutor may ever face. The multitude of factors found in many licit drugged driving cases provide the defense with ample opportunity to conduct an appeal to the jurors’ hearts and minds and to derogate the prosecution’s evidence. Addressing the identification bias commonly found in licit drug DUI cases exposes any entitlement defense and eliminates any technical defenses. The prosecutor has the op-opportunity to enlighten and empower the finder of fact to recognize and reject the defense’s strategies in an objective, rational, and principled manner.
Driving and legal drug use are near universal in our society. As such, jurors have an instant commonality with the defendant that brings with it both conscious and subconscious self-identification influences. Jurors who empathize with a defendant may go to great lengths to acquit. When a juror can envision himself ending up in the defendant’s chair or thinks “there but for the grace of God go I,” the prosecutor has an identification bias issue that must be confronted.
The defense does not need to explicitly raise the identification bias in favor of the defendant. While most jurors cannot identify with other criminal behavior, they may have little difficulty identifying and empathizing with an otherwise law-abiding citizen who finds himself accused of driving under the influence. However, few potential jurors may feel a kinship with people accused of driving under the influence of illicit drugs like heroin, cocaine or methamphetamine. But, in cases involving OTC and commonly pre- scribed drugs, the biases can be particularly strong and easily exploited by the defense. The presence of a doctor’s prescription often weights the balance heavily in favor of the defense.
Long-running campaigns to create and increase public awareness of the dangers of drunk driving have been successful. These campaigns have created a mindset in most 7

people that reflexively equates drinking and driving with “bad behavior.” As a result, many jurors may consciously or subconsciously separate themselves from the accused sit- ting before them when the accusation is drunk driving. Few public awareness campaigns currently exist to educate the public about the dangers of drugged driving. There is no readily recognizable licit drugged driving message that a prosecutor can invoke to men- tally distance the jurors from the defendant. As a result the prosecutor must attempt to show these behavioral differences between the jurors and the defendant.
Prosecutors use voir dire ostensibly to eliminate from the jury panel those individuals who are unable, for whatever reason, to serve as fair and impartial jurors. In licit drug DUIs, the prosecutor must use voir dire to uncover conscious and subconscious biases for the defendant. For example, the prosecutor might ask potential jurors if they take prescription and OTC medicines, and if they operate motor vehicles after taking such medications. This line of questioning identifies those jurors who may have possible conscious and subconscious biases.
Subsequently, the prosecutor may inquire if the jurors are aware that DUI is a crime of personal responsibility. For example, it is legal to drink and drive and a person of legal age does not need a prescription to drink alcohol. What is illegal is driving while impaired. It does not matter if the impairment is caused by alcohol, legal drugs, or illegal drugs. What matters is the decision on the part of the person to get behind the wheel of an automobile while impaired. That decision is fundamental to all DUIs.
Impaired drivers often contend that they thought that they were okay to drive. This mindset forms the core of the entitlement defense. The law does not recognize “I thought I was okay to drive” as a legitimate defense. Yet, it gets put before the jury in a great many drug DUI cases. Whether the defendant thought he was okay to drive or was even aware of the true magnitude of his impairment is not one of the facts that the jury is asked to decide. Often jurors will reject the notion of whether a person thinks he or she is okay to drive as a deciding factor in a DUI case. Many jurors will respond with statements such as “he should have known better” and “he was just fooling himself.” Those expressions of thought and belief play up the personal responsibility theme and aid in neutralizing the identification bias inherent in drug DUIs. 8

Breath Testing Results: Defense Alternative Explanations
Diabetes
A classic defense in impaired driving cases is to claim the officer mistakenly attributed signs of alcohol impairment to that of a diabetic reaction. Although a common medical condition, diabetes is often misunderstood and misrepresented by the defense. Understanding the disease and its effects on the body will allow prosecutors to dispel the notion diabetics are being wrongfully convicted in DUI cases.
Type 1 Diabetes versus Type 2 Diabetes
Diabetes is a disease in which the body does not produce or properly use insulin. Insulin is a hormone made by the pancreas and its function is to convert the food a person eats into energy needed to sustain daily life. There are two main types of diabetes: Type 1 and Type 2.
Type 1 diabetes, previously known as juvenile diabetes, is usually diagnosed in children and young adults. In Type 1 diabetes, the body does not produce the hormone insulin that is needed to convert sugar (glucose), starches, and other food into energy. Only 5- to 10% of people with diabetes have this form of the disease. This fact is important to remember when we later talk about the substance “acetone.”
Type 2 diabetes, previously known as adult onset diabetes, is the most common form of diabetes and accounts for 90- to 95% of all cases. In Type 2 diabetes, the body either does not produce enough insulin or the cells simply ignore the insulin. When glucose builds up in the blood instead of entering the cells, it immediately starves the cells of energy and over time may damage the person’s eyes, kidneys, nerves, or heart.
Hypoglycemia versus Hyperglycemia
When the diabetes defense is raised, the most important distinction for the prosecutor to recognize is the difference between hypoglycemia and hyperglycemia. Either condition can happen to diabetics from time to time. However, the effects of hypoglycemia (low blood glucose) are much different than the effects of hyperglycemia (high blood glucose). The defense will try to intermingle the two conditions to create a story most advantageous to their client.
Hypoglycemia occurs when blood glucose (or blood sugar) concentrations fall be-low a level necessary to properly support the body’s need for energy throughout its cells. It is often referred to as an insulin reaction because the body either has too much insulin, meals and snacks are missed, or there is an increase of physical activity or exercise. Furthermore, hypoglycemia can occur if a diabetic injects too much insulin, resulting in insulin shock. 9

Some of the symptoms of hypoglycemia and alcohol impairment can be similar – slurred speech, dizziness, and disorientation. The onset of hypoglycemia is rapid. Left untreated, it can result in loss of consciousness and/or seizure activity. Unlike signs of alcohol impairment, the symptoms of hypoglycemia will not dissipate over time. Treatment is required for the person to get better. It should also be noted hypoglycemia does not pro-duce a fruity smell to the breath and will not cause a false positive and/or elevate a breath alcohol test result.
Hyperglycemia occurs when blood glucose concentrations are high. This happens when the body has too little insulin or when the body cannot use insulin properly. The on-set of hyperglycemia is slow. The signs of hyperglycemia include feeling thirsty, constant urination, and a dry mouth. Hyperglycemia will not cause impaired behavior that mimics intoxication in the same manner that hypoglycemia will.
If left untreated, hyperglycemia can lead to a condition called ketoacidosis. This is a serious condition that can lead to a diabetic coma or even death. Ketoacidosis develops when your body does not have enough insulin. Without insulin, the body is not able to use glucose and will begin to burn fat for energy, which produces ketones. Ketones are acids that build up in the blood and appear in the urine. This is a warning that the diabetes is out of control or the person is otherwise getting sick.
Ketoacidosis can produce a fruity acetone-like smell to the person’s breath. It is a smell much different than the smell of beer, bourbon or other alcoholic drinks. It is claimed this fruity smell can be mistaken for alcohol, but most officers should be able to tell the difference. In fact, if the officer detects a fruity smell on the person’s breath at roadside, it would be expected the person would appear to be very ill. The person could be vomiting and exhibiting signs of fatigue, difficulty breathing (shallow), and confusion. Ketoacidosis is a very serious condition.
Note: Ketosis may exist for conditions other than diabetes. Ketoacidosis is rare in people with Type 2 diabetes. It is most common in people with Type 1 diabetes who have taken too little insulin. Remember, only 5 to 10% of people with diabetes have Type 1 diabetes. 10


Characteristic
Hypoglycemia
Hyperglycemia
Onset
Rapid (minutes)
Gradual (days)
Mood
Labile, irritable, nervous, weepy, combative
Lethargic
Mental status
Difficulty concentrating, speak-ing, focusing, coordinating
Dulled sensorium, confused
Inward feeling
Shaking feeling, hunger, headache, dizziness
Thirst, weakness, nausea/
vomiting, abdominal pain
Skin
Pallor, sweating
Flushed, signs of dehydration
Mucus membranes
Normal
Dry, crusty
Respiration
Shallow
Deep, rapid (Kussmaul)
Pulse
Tachycardia
Less rapid, weak
Breath odor
Normal
Fruity, acetone
Neurologic
Tremors late: hyperreflexia, dilated pupils, convulsion
Paresthesia
Ominous signs
Shock, coma
Acidosis, coma
Blood
Glucose
Ketones Osmolarity pH Hema-tocrit HCO3
Low: below 70 mg/dl Negative/trace Nor-mal
Normal Normal Normal
High: 240 mg/dl or more High/large (only if DKA) High
Low (7.25 or less) High
Less than 15eEq/L
Urine: Output
Sugar
Acetone
Normal Negative Negative/trace
Polyuria to oliguria
High
High











































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